Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome.
To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 in X-inactivation. Xist exon 7 is the second-largest exon with a well-conserved repeat E in eutherian mammals, but its role...
मुख्य लेखकों: | , , , , , |
---|---|
स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
Public Library of Science (PLoS)
2015-08-01
|
श्रृंखला: | PLoS Genetics |
ऑनलाइन पहुंच: | http://europepmc.org/articles/PMC4526699?pdf=render |