Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome.

To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 in X-inactivation. Xist exon 7 is the second-largest exon with a well-conserved repeat E in eutherian mammals, but its role...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Norishige Yamada, Yuko Hasegawa, Minghui Yue, Tomofumi Hamada, Shinichi Nakagawa, Yuya Ogawa
स्वरूप: लेख
भाषा:English
प्रकाशित: Public Library of Science (PLoS) 2015-08-01
श्रृंखला:PLoS Genetics
ऑनलाइन पहुंच:http://europepmc.org/articles/PMC4526699?pdf=render