Neutrophils in Cancer immunotherapy: friends or foes?

Neutrophils in Cancer immunotherapy: friends or foes?

Abstract Neutrophils play a Janus-faced role in the complex landscape of cancer pathogenesis and immunotherapy. As immune defense cells, neutrophils release toxic substances, including reactive oxygen species and matrix metalloproteinase 9, within the tumor microenvironment. They also modulate the e...

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Bibliographic Details
Main Authors: Xueqin Huang, Eugenie Nepovimova, Vojtech Adam, Ladislav Sivak, Zbynek Heger, Marian Valko, Qinghua Wu, Kamil Kuca
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Molecular Cancer
Subjects:
Neutrophils
Cancer
Immunotherapy
Antitumor activity
Protumor activity
Online Access:https://doi.org/10.1186/s12943-024-02004-z

Internet

https://doi.org/10.1186/s12943-024-02004-z

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