CAR‐T‐cell products in solid tumors: Progress, challenges, and strategies

CAR‐T‐cell products in solid tumors: Progress, challenges, and strategies

Abstract T cells engineered to express chimeric antigen receptors (CARs) with specificity toward tumor cells have led to promising outcomes in patients with hematological malignancies. Nevertheless, the application of CAR‐T cell therapy in solid tumors encounters several obstacles. These include tum...

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Bibliographic Details
Main Authors: Kewen Qian, Guangyao Li, Shuyi Zhang, Wenyan Fu, Tian Li, Jian Zhao, Changhai Lei, Yuqing Wang, Shi Hu
Format: Article
Language:English
Published: Wiley-VCH 2024-04-01
Series:Interdisciplinary Medicine
Subjects:
cancer therapy
CAR‐T
chimeric antigen receptor
solid tumor
tumor microenvironment
Online Access:https://doi.org/10.1002/INMD.20230047

Internet

https://doi.org/10.1002/INMD.20230047

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