Glycyrrhizic acid rebalances mitochondrial dynamics to mitigate hepatotoxicity induced by triptolide

Glycyrrhizic acid rebalances mitochondrial dynamics to mitigate hepatotoxicity induced by triptolide

Triptolide (TP) has various pharmacological activities, but its hepatotoxicity limits its therapeutic potential. Licorice has been evaluated to harmonize various medicines, and its active ingredient glycyrrhizic acid (GA) has been identified for its detoxification effect. In this study, we demonstra...

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Bibliographic Details
Main Authors: Zhiwen Cao, Bin Liu, Lan Yan, Haiyang Shu, Lili Wang, Li Li, Peipei Lu, Xiaojuan He, Guilin Ouyang, Zhixin Nie, Aiping Lu, Cheng Lu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Functional Foods
Subjects:
Mitochondrial dynamics
Hepatotoxicity
Glycyrrhizic acid
Triptolide
PKCα
FIS1
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624000082

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http://www.sciencedirect.com/science/article/pii/S1756464624000082

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