Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

Suppressive function of regulatory T cells (Treg) is dependent on signaling of their antigen receptors triggered by cognate self, dietary, or microbial peptides presented on MHC II. However, it remains largely unknown whether distinct or shared repertoires of Treg TCRs are mobilized in response to d...

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Bibliographic Details
Main Authors: Tatyana O Nakonechnaya, Bruno Moltedo, Ekaterina V Putintseva, Sofya Leyn, Dmitry A Bolotin, Olga V Britanova, Mikhail Shugay, Dmitriy M Chudakov
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-04-01
Series:eLife
Subjects:
TCR repertoire
lung challenges
treg
CD4+ T cells
antigenic specificity
homing
Online Access:https://elifesciences.org/articles/89382

Internet

https://elifesciences.org/articles/89382

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