Engineering of a bona fide light-operated calcium channel

Engineering of a bona fide light-operated calcium channel

Existing optogenetic methods to induce calcium mobilisation lack selectivity and specificity. Here, the authors design and engineer a single-component light-operated calcium channel to provide optical control over calcium signals and calcium-dependent physiological responses: LOCa.

Bibliographic Details
Main Authors: Lian He, Liuqing Wang, Hongxiang Zeng, Peng Tan, Guolin Ma, Sisi Zheng, Yaxin Li, Lin Sun, Fei Dou, Stefan Siwko, Yun Huang, Youjun Wang, Yubin Zhou
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20425-4

Internet

https://doi.org/10.1038/s41467-020-20425-4

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