Engineering of a bona fide light-operated calcium channel
Existing optogenetic methods to induce calcium mobilisation lack selectivity and specificity. Here, the authors design and engineer a single-component light-operated calcium channel to provide optical control over calcium signals and calcium-dependent physiological responses: LOCa.
Bibliographic Details
| Main Authors: |
Lian He,
Liuqing Wang,
Hongxiang Zeng,
Peng Tan,
Guolin Ma,
Sisi Zheng,
Yaxin Li,
Lin Sun,
Fei Dou,
Stefan Siwko,
Yun Huang,
Youjun Wang,
Yubin Zhou |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-01-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-20425-4
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