Engineering of a bona fide light-operated calcium channel
Existing optogenetic methods to induce calcium mobilisation lack selectivity and specificity. Here, the authors design and engineer a single-component light-operated calcium channel to provide optical control over calcium signals and calcium-dependent physiological responses: LOCa.
Main Authors: | Lian He, Liuqing Wang, Hongxiang Zeng, Peng Tan, Guolin Ma, Sisi Zheng, Yaxin Li, Lin Sun, Fei Dou, Stefan Siwko, Yun Huang, Youjun Wang, Yubin Zhou |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-20425-4 |
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