Expression of minor cartilage collagens and small leucine rich proteoglycans may be relatively reduced in osteoarthritic cartilage

Expression of minor cartilage collagens and small leucine rich proteoglycans may be relatively reduced in osteoarthritic cartilage

Abstract Background In osteoarthritis (OA), cartilage matrix is lost despite vigorous chondrocyte anabolism. In this study, we attempted to determine whether altered matrix synthesis is involved in this paradox in disease progression through gene expression analysis and ultrastructural analysis of c...

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Manylion Llyfryddiaeth
Prif Awduron:	Nobuho Tanaka, Toshiyuki Tashiro, Yozo Katsuragawa, Motoji Sawabe, Hiroshi Furukawa, Naoshi Fukui
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	BMC 2019-05-01
Cyfres:	BMC Musculoskeletal Disorders
Pynciau:	Osteoarthritis Articular cartilage Collagen Small leucine rich proteoglycan Collagen fibril formation Transmission electron mocroscopy
Mynediad Ar-lein:	http://link.springer.com/article/10.1186/s12891-019-2596-y

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