Expression of minor cartilage collagens and small leucine rich proteoglycans may be relatively reduced in osteoarthritic cartilage

Abstract Background In osteoarthritis (OA), cartilage matrix is lost despite vigorous chondrocyte anabolism. In this study, we attempted to determine whether altered matrix synthesis is involved in this paradox in disease progression through gene expression analysis and ultrastructural analysis of c...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Nobuho Tanaka, Toshiyuki Tashiro, Yozo Katsuragawa, Motoji Sawabe, Hiroshi Furukawa, Naoshi Fukui
التنسيق: مقال
اللغة:English
منشور في: BMC 2019-05-01
سلاسل:BMC Musculoskeletal Disorders
الموضوعات:
الوصول للمادة أونلاين:http://link.springer.com/article/10.1186/s12891-019-2596-y