Link N as a therapeutic agent for discogenic pain

Neurotrophins (NTs) are the major contributors of sensory axonal sprouting, neural survival, regulation of nociceptive sensory neurons, inflammatory hyperalgesia, and neuropathic pain. Intervertebral disc (IVD) cells constitutively express NTs. Their expression is upregulated by proinflammatory cyto...

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Bibliographic Details
Main Authors: Hussain Noorwali, Michael P. Grant, Laura M. Epure, Padma Madiraju, Hee‐Jeong Sampen, John Antoniou, Fackson Mwale
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:JOR Spine
Subjects:
Online Access:https://doi.org/10.1002/jsp2.1008