Profiling disease and tissue-specific epigenetic signatures in cell-free DNA

Programmed cell death, accidental cell degradation and active extrusion constantly lead to the release of DNA fragments into human body fluids from virtually all cell and tissue types. It is widely accepted that these cell-free DNA (cfDNA) molecules retain the cell-type specific genetic and epigenet...

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Bibliographic Details
Main Authors: Oberhofer Angela, Bronkhorst Abel Jacobus, Ungerer Vida, Holdenrieder Stefan
Format: Article
Language:English
Published: De Gruyter 2022-08-01
Series:Journal of Laboratory Medicine
Subjects:
Online Access:https://doi.org/10.1515/labmed-2022-0031