Profiling disease and tissue-specific epigenetic signatures in cell-free DNA
Programmed cell death, accidental cell degradation and active extrusion constantly lead to the release of DNA fragments into human body fluids from virtually all cell and tissue types. It is widely accepted that these cell-free DNA (cfDNA) molecules retain the cell-type specific genetic and epigenet...
Main Authors: | Oberhofer Angela, Bronkhorst Abel Jacobus, Ungerer Vida, Holdenrieder Stefan |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2022-08-01
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Series: | Journal of Laboratory Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1515/labmed-2022-0031 |
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