Confirmation of high-throughput screening data and novel mechanistic insights into FXR-xenobiotic interactions by orthogonal assays

Toxicology in the 21st Century (Tox21) is a federal collaboration employing a high-throughput robotic screening system to test 10,000 environmental chemicals. One of the primary goals of the program is prioritizing toxicity evaluations through in vitro high-throughput screening (HTS) assays for larg...

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Bibliographic Details
Main Authors: Jon Hamm, Debabrata Mahapatra, Megan M. Knuth, Jaleh Abedini, Mary Lingerfelt, Sean Ekins, Seth W. Kullman
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Toxicology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X22000299

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