Analysis of the human kinome using methods including fold recognition reveals two novel kinases.
Protein sequence similarity is a commonly used criterion for inferring the unknown function of a protein from a protein of known function. However, proteins can diverge significantly over time such that sequence similarity is difficult, if not impossible, to find. In some cases, a structural similar...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-02-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2223070?pdf=render |