Bio-physiological susceptibility of the brain, heart, and lungs to systemic ischemia reperfusion and hyperoxia-induced injury in post-cardiac arrest rats
Abstract Cardiac arrest (CA) patients suffer from systemic ischemia–reperfusion (IR) injury leading to multiple organ failure; however, few studies have focused on tissue-specific pathophysiological responses to IR-induced oxidative stress. Herein, we investigated biological and physiological parame...
Main Authors: | Tomoaki Aoki, Vanessa Wong, Yusuke Endo, Kei Hayashida, Ryosuke Takegawa, Yu Okuma, Muhammad Shoaib, Santiago J. Miyara, Tai Yin, Lance B. Becker, Koichiro Shinozaki |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-30120-1 |
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