Computational analysis of splicing errors and mutations in human transcripts

<p>Abstract</p> <p>Background</p> <p>Most retained introns found in human cDNAs generated by high-throughput sequencing projects seem to result from underspliced transcripts, and thus they capture intermediate steps of pre-mRNA splicing. On the other hand, mutations in...

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Bibliographic Details
Main Authors: Gelfand Mikhail S, Kurmangaliyev Yerbol Z
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/13