Post-Translational Modifications of STING: A Potential Therapeutic Target

Post-Translational Modifications of STING: A Potential Therapeutic Target

Stimulator of interferon genes (STING) is an endoplasmic-reticulum resident protein, playing essential roles in immune responses against microbial infections. However, over-activation of STING is accompanied by excessive inflammation and results in various diseases, including autoinflammatory diseas...

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Bibliographic Details
Main Authors: Jiaqi Kang, Jie Wu, Qinjie Liu, Xiuwen Wu, Yun Zhao, Jianan Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
STING
post translational modification
targeted therapy
diseases
phosphorylation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.888147/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.888147/full

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