Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages

Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages

Atherosclerosis is a process of imbalanced lipid metabolism in the vascular walls. The underlying pathology mainly involves the deposition of oxidized lipids in the endothelium and the accumulation of cholesterol in macrophages. Macrophages export excessive cholesterol (cholesterol efflux) through A...

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Bibliographic Details
Main Authors: I-Jou Teng, Min-Chien Tsai, Shao-Fu Shih, Bi-Feng Tsuei, Hsin Chang, Yi-Ping Chuang, Chin-Sheng Lin, Ching-Yuh Chern, Sy-Jou Chen
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
atherosclerosis
cholesterol efflux
ATP-binding cassette transporters A1
chalcone derivative
Online Access:http://www.mdpi.com/1420-3049/23/7/1620

Internet

http://www.mdpi.com/1420-3049/23/7/1620

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