Epigenetic Application of ATAC-Seq Based on Tn5 Transposase Purification Technology

Background. Assays of transposase accessible chromatin sequencing (ATAC-seq) is an efficient assay to investigate chromatin accessibility, which depends on the activity of a robust Tn5 transposase to fragment the genome while cutting in the sequencing adapters. Methods. We propose reliable approache...

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Bibliographic Details
Main Authors: Wangchun Li, U Tim Wu, Yu Cheng, Yanhao Huang, Lipeng Mao, Menghan Sun, Congling Qiu, Lin Zhou, Lijuan Gao
Format: Article
Language:English
Published: Hindawi - Cambridge University Press 2022-01-01
Series:Genetics Research
Online Access:http://dx.doi.org/10.1155/2022/8429207