Genomic investigation unveils colistin resistance mechanism in carbapenem-resistant Acinetobacter baumannii clinical isolates

Genomic investigation unveils colistin resistance mechanism in carbapenem-resistant Acinetobacter baumannii clinical isolates

ABSTRACTColistin resistance in Acinetobacter baumannii is mediated by multiple mechanisms. Recently, mutations within pmrABC two-component system and overexpression of eptA gene due to upstream insertion of ISAba1 have been shown to play a major role. Thus, the aim of our study is to characterize co...

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Bibliographic Details
Main Authors: Saranya Vijayakumar, Rayapadi G. Swetha, Yamuna Devi Bakthavatchalam, Karthick Vasudevan, Baby Abirami Shankar, Agilandeeswari Kirubananthan, Kamini Walia, Sudha Ramaiah, Indranil Biswas, Balaji Veeraraghavan, Anand Anbarasu
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:Microbiology Spectrum
Subjects:
Acinetobacter baumannii
colistin
resistance
SNP
lpx
pmr
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02511-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02511-23

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