The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

<p>Abstract</p> <p>Background</p> <p>The fibroblast growth factor receptor (FGFR) interprets concentration gradients of FGF ligands and structural changes in the heparan sulfate (HS) co-receptor to generate different cellular responses. However, whether the FGFR generat...

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Bibliographic Details
Main Authors: Duchesne Laurence, Zhu Hongyan, Rudland Philip S, Fernig David G
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Cell Communication and Signaling
Online Access:http://www.biosignaling.com/content/8/1/14

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http://www.biosignaling.com/content/8/1/14

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