Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-delivered Genetic Adjuvants

Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-delivered Genetic Adjuvants

In recent years, DNA vaccines have undergone a number of technological advancements that have incited renewed interest and heightened promise in the field. Two such improvements are the use of genetically engineered cytokine adjuvants and plasmid delivery via in vivo electroporation (EP), the latter...

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Bibliographic Details
Main Authors: Seleeke eFlingai, Matias eCzerwonko, Jonathan eGoodman, Sagar B Kudchodkar, Kar eMuthumani, David B Weiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Immunology
Subjects:
Electroporation
Interleukin-12
adjuvants
DNA vaccine
Plasmid
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00354/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00354/full

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