Identification of quantitative polymerase chain reaction reference genes suitable for normalising gene expression in the brain of normal and dystrophic mice and dogs [version 2; peer review: 2 approved, 1 approved with reservations]
Background: In addition to progressive, debilitating muscle degeneration, ~50% of patients with Duchenne muscular dystrophy (DMD) have associated cognitive and behavioural disorders secondary to deficiency of dystrophin protein in the brain. The brain expresses a variety of dystrophin isoforms (Dp42...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2023-05-01
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Series: | Wellcome Open Research |
Subjects: | |
Online Access: | https://wellcomeopenresearch.org/articles/6-84/v2 |