Identification of quantitative polymerase chain reaction reference genes suitable for normalising gene expression in the brain of normal and dystrophic mice and dogs [version 2; peer review: 2 approved, 1 approved with reservations]

Background: In addition to progressive, debilitating muscle degeneration, ~50% of patients with Duchenne muscular dystrophy (DMD) have associated cognitive and behavioural disorders secondary to deficiency of dystrophin protein in the brain. The brain expresses a variety of dystrophin isoforms (Dp42...

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Bibliographic Details
Main Authors: Abbe H. Crawford, Dominic J. Wells, John C. W. Hildyard, Richard J. Piercy
Format: Article
Language:English
Published: Wellcome 2023-05-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/6-84/v2