Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries

Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries

Fenestrated and blood-brain barrier (BBB)-forming endothelial cells constitute major brain capillaries, and this vascular heterogeneity is crucial for region-specific neural function and brain homeostasis. How these capillary types emerge in a brain region-specific manner and subsequently establish...

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Bibliographic Details
Main Authors: Sweta Parab, Olivia A Card, Qiyu Chen, Michelle America, Luke D Buck, Rachael E Quick, William F Horrigan, Gil Levkowitz, Benoit Vanhollebeke, Ryota L Matsuoka
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
Subjects:
brain angiogenesis
central nervous system
vascular heterogeneity
fenestrated endothelial cells
Vegfs
Wnts
Online Access:https://elifesciences.org/articles/86066

Internet

https://elifesciences.org/articles/86066

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