Long term physicochemical stability study of novel ophthalmic formulations combining ceftazidime and vancomycin with and without cyclodextrins
Ceftazidime (CZ) and Vancomycin (VM) are used to treat bacterial keratitis; however, their physicochemical incompatibility does not allow their co-administration. This incompatibility can be managed by buffering the mixture at an alkaline pH or by using cage molecules such as cyclodextrins (CD). The...
Main Authors: | Plaidy Pauline, Bouattour Yassine, Yessaad Mouloud, Sautou Valérie, Chennell Philip |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2023-09-01
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Series: | Pharmaceutical Technology in Hospital Pharmacy |
Subjects: | |
Online Access: | https://doi.org/10.1515/pthp-2023-0007 |
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