An in vivo model of ligamentum flavum hypertrophy from early‐stage inflammation to fibrosis

An in vivo model of ligamentum flavum hypertrophy from early‐stage inflammation to fibrosis

Abstract Multi‐joint disease pathologies in the lumbar spine, including ligamentum flavum (LF) hypertrophy and intervertebral disc (IVD) bulging or herniation contribute to lumbar spinal stenosis (LSS), a highly prevalent condition characterized by symptomatic narrowing of the spinal canal. Clinical...

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Bibliographic Details
Main Authors: Kevin G. Burt, Dan C. Viola, Lauren E. Lisiewski, Joseph M. Lombardi, Louis F. Amorosa, Nadeen O. Chahine
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:JOR Spine
Subjects:
fibrosis
histological analysis
hypertrophy
inflammation
ligamentum flavum
rat model
Online Access:https://doi.org/10.1002/jsp2.1260

Internet

https://doi.org/10.1002/jsp2.1260

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