Metagenomic next-generation sequencing versus traditional laboratory methods for the diagnosis of central nervous system opportunistic infections in HIV-infected Chinese adults

Metagenomic next-generation sequencing versus traditional laboratory methods for the diagnosis of central nervous system opportunistic infections in HIV-infected Chinese adults

Abstract To evaluate clinical value of metagenomic next-generation sequencing (mNGS) in people living with HIV/AIDS (PLWHA) who had CNS disorders. Cerebrospinal fluid (CSF) samples from 48 PLWHA presenting with CNS disorders were sequenced using mNGS and compared with clinical conventional diagnosti...

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Bibliographic Details
Main Authors: Liping Deng, Qian Li, Wenjia Hu, Xiaoping Chen, Tielong Chen, Shihui Song, Pingzheng Mo, Shi Zou, Yongxi Zhang, Shicheng Gao, Liangjun Chen, Ke Zhuang, Rongrong Yang, Yong Xiong
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31974-1

Internet

https://doi.org/10.1038/s41598-023-31974-1

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