The pancreas is altered by in utero androgen exposure: implications for clinical conditions such as polycystic ovary syndrome (PCOS).

The pancreas is altered by in utero androgen exposure: implications for clinical conditions such as polycystic ovary syndrome (PCOS).

Using an ovine model of polycystic ovary syndrome (PCOS), (pregnant ewes injected with testosterone propionate (TP) (100 mg twice weekly) from day (d)62 to d102 of d147 gestation (maternal injection - MI-TP)), we previously reported female offspring with normal glucose tolerance but hyperinsulinemia...

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Bibliographic Details
Main Authors: Mick Rae, Cathal Grace, Kirsten Hogg, Lisa Marie Wilson, Sophie L McHaffie, Seshadri Ramaswamy, Janis MacCallum, Fiona Connolly, Alan S McNeilly, Colin Duncan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3574134?pdf=render

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http://europepmc.org/articles/PMC3574134?pdf=render

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