Chaihu Shugan powder alleviates liver inflammation and hepatic steatosis in NAFLD mice: A network pharmacology study and in vivo experimental validation

Chaihu Shugan powder alleviates liver inflammation and hepatic steatosis in NAFLD mice: A network pharmacology study and in vivo experimental validation

Background: Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic disease and is intertwined with cardiovascular disorders and diabetes. Chaihu Shugan powder (CSP) is a traditional Chinese medicine with a significant therapeutic effect on metabolic diseases, such as NAFLD. However, i...

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Bibliographic Details
Main Authors: Sisi Lei, Shuai Zhao, Xiaoyan Huang, Yuchao Feng, Zhishang Li, Li Chen, Peiying Huang, Hansu Guan, Haobo Zhang, Qihua Wu, Bojun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
chaihu shugan powder
nonalcoholic fatty liver disease
inflammation
systems pharmacology
fatty acid synthesis
TNFα/TNFR1 pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.967623/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.967623/full

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