Efficacy of selenium supplementation for mild-to-moderate Graves’ ophthalmopathy in a selenium-sufficient area (SeGOSS trial): study protocol for a phase III, multicenter, open-label, randomized, controlled intervention trial

Abstract Background The therapeutic effect of selenium has been demonstrated in mild Graves’ ophthalmopathy (GO) in a European region where selenium status is suboptimal. However, there is a lack of evidence to support selenium use in selenium-sufficient areas. The aim of this study is to evaluate t...

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Bibliographic Details
Main Authors: Chae Won Chung, Kyong Yeun Jung, Eun Hye Jung, Min Joung Lee, Young Joo Park, Jeong Kyu Lee, Hwa Young Ahn, Sun Wook Cho
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-023-07282-4