Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection

Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection

Unlike other MAC members, Mycobacterium avium subsp. paratuberculosis (MAP) does not produce glycopeptidolipids (GPL) on the surface of the cell wall but a lipopentapeptide called L5P (also termed Lipopeptide-I or Para-LP-01) characterized in C-type (bovine) strains. This lipopeptide antigen contain...

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Bibliographic Details
Main Authors: Sylvie Bay, Douglas Begg, Christelle Ganneau, Maxime Branger, Thierry Cochard, John P. Bannantine, Heike Köhler, Jean-Louis Moyen, Richard J. Whittington, Franck Biet
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Veterinary Science
Subjects:
Mycobacterium avium subsp. paratuberculosis
Johne's disease
lipopeptide
diagnosis
antibody response
chemical synthesis
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.637841/full

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https://www.frontiersin.org/articles/10.3389/fvets.2021.637841/full

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