Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis.

Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis.

African trypanosomiasis is a deadly neglected disease caused by the extracellular parasite Trypanosoma brucei. Current therapies are characterized by high drug toxicity and increasing drug resistance mainly associated with loss-of-function mutations in the transporters involved in drug import. The i...

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Bibliographic Details
Main Authors: Juan D Unciti-Broceta, José L Arias, José Maceira, Miguel Soriano, Matilde Ortiz-González, José Hernández-Quero, Manuel Muñóz-Torres, Harry P de Koning, Stefan Magez, José A Garcia-Salcedo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004942

Internet

https://doi.org/10.1371/journal.ppat.1004942

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