Coumarin-Based Triapine Derivatives and Their Copper(II) Complexes: Synthesis, Cytotoxicity and mR2 RNR Inhibition Activity

Coumarin-Based Triapine Derivatives and Their Copper(II) Complexes: Synthesis, Cytotoxicity and mR2 RNR Inhibition Activity

A series of thiosemicarbazone-coumarin hybrids (<b>HL<sup>1</sup>-HL<sup>3</sup></b> and <b>H<sub>2</sub>L<sup>4</sup></b>) has been synthesised in 12 steps and used for the preparation of mono- and dinuclear copper(II) complexe...

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Bibliographic Details
Main Authors: Iryna Stepanenko, Maria V. Babak, Gabriella Spengler, Marta Hammerstad, Ana Popovic-Bijelic, Sergiu Shova, Gabriel E. Büchel, Denisa Darvasiova, Peter Rapta, Vladimir B. Arion
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
triapine
coumarin
thiosemicarbazones
copper(II)
electrochemistry
antiproliferative activity
Online Access:https://www.mdpi.com/2218-273X/11/6/862

Internet

https://www.mdpi.com/2218-273X/11/6/862

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