Identification of therapeutic targets for osteosarcoma by integrating single-cell RNA sequencing and network pharmacology

Identification of therapeutic targets for osteosarcoma by integrating single-cell RNA sequencing and network pharmacology

Background: Osteosarcoma (OS) is a common primary tumor with extensive heterogeneity. In this study, we used single-cell RNA sequencing (scRNA-seq) and network pharmacology to analyze effective targets for Osteosarcoma treatment.Methods: The cell heterogeneity of the Osteosarcoma single-cell dataset...

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Bibliographic Details
Main Authors: Yan Wang, Di Qin, Yiyao Gao, Yunxin Zhang, Yao Liu, Lihong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
osteosarcoma
single-cell RNA sequencing
network pharmacology
molecular docking
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1098800/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1098800/full

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