miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6

miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6

miR-128, a brain-enriched microRNA, has been implicated in the control of neurogenesis and synaptogenesis but its potential roles in intervening processes have not been addressed. We show that post-transcriptional mechanisms restrict miR-128 accumulation to post-mitotic neurons during mouse corticog...

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Bibliographic Details
Main Authors: Eleonora Franzoni, Sam A Booker, Srinivas Parthasarathy, Frederick Rehfeld, Sabine Grosser, Swathi Srivatsa, Heiko R Fuchs, Victor Tarabykin, Imre Vida, F Gregory Wulczyn
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-01-01
Series:eLife
Subjects:
Börjeson-Forssman-Lehmann syndrome
cortical development
developmental timing
post-translational gene regulation
Online Access:https://elifesciences.org/articles/04263

Internet

https://elifesciences.org/articles/04263

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