Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor

Most cases of preterm labor have unknown cause, and the burden of preterm birth is immense. Placental aging has been proposed to promote labor onset, but specific mechanisms remain elusive. We report findings stemming from unbiased transcriptomic analysis of mouse placenta, which revealed that hypox...

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Bibliographic Details
Main Authors: Erin J Ciampa, Padraich Flahardy, Harini Srinivasan, Christopher Jacobs, Linus Tsai, S Ananth Karumanchi, Samir M Parikh
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/85597