Dynamics of hepatocyte-cholangiocyte cell-fate decisions during liver development and regeneration

Summary: The immense regenerative potential of the liver is attributed to the ability of its two key cell types – hepatocytes and cholangiocytes – to trans-differentiate to one another either directly or through intermediate progenitor states. However, the dynamic features of decision-making between...

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Bibliographic Details
Main Authors: Sarthak Sahoo, Ashutosh Mishra, Anna Mae Diehl, Mohit Kumar Jolly
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222012275