SLAMF8 Downregulates Mouse Macrophage Microbicidal Mechanisms via PI3K Pathways

SLAMF8 Downregulates Mouse Macrophage Microbicidal Mechanisms via PI3K Pathways

Signaling lymphocytic activation molecule family 8 (SLAMF8) is involved in the negative modulation of NADPH oxidase activation. However, the impact of SLAMF8 downregulation on macrophage functionality and the microbicide mechanism remains elusive. To study this in depth, we first analyzed NADPH oxid...

Full description

Bibliographic Details
Main Authors: Salvador Romero-Pinedo, Domingo I. Rojas Barros, María José Ruiz-Magaña, Elena Maganto-García, Laura Moreno de Lara, Francisco Abadía-Molina, Cox Terhorst, Ana C. Abadía-Molina
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
SLAMF8
macrophages
SLAMF
PI3K signaling pathway
Salmonella typhimurium
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.910112/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.910112/full

Similar Items