SMPDL3B Predicts Poor Prognosis and Contributes to Development of Acute Myeloid Leukemia

SMPDL3B Predicts Poor Prognosis and Contributes to Development of Acute Myeloid Leukemia

Background: Acute myeloid leukemia (AML), characterized by the low cure rate and high relapse, urgently needs novel diagnostic or prognostic biomarkers and potential therapeutic targets. Sphingomyelin Phosphodiesterase Acid Like 3B (SMPDL3B) is a negative regulator of Toll-like receptor signaling th...

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Bibliographic Details
Main Authors: Huiqing Qu, Ye Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
acute myeloid leukemia
biomarker
SMPDL3B
prognosis
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.695601/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.695601/full

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