Surface antibody changes protein corona both in human and mouse serum but not final opsonization and elimination of targeted polymeric nanoparticles

Surface antibody changes protein corona both in human and mouse serum but not final opsonization and elimination of targeted polymeric nanoparticles

Abstract Background Nanoparticles represent one of the most important innovations in the medical field. Among nanocarriers, polymeric nanoparticles (PNPs) attracted much attention due to their biodegradability, biocompatibility, and capacity to increase efficacy and safety of encapsulated drugs. Ano...

Full description

Bibliographic Details
Main Authors: Sara Capolla, Federico Colombo, Luca De Maso, Prisca Mauro, Paolo Bertoncin, Thilo Kähne, Alexander Engler, Luis Núñez, Ruben Spretz, Gustavo Larsen, Michele Dal Bo, Giuseppe Toffoli, Paolo Macor
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Nanobiotechnology
Subjects:
Polymeric nanoparticles
Mouse serum
Human serum
Human plasma
Complement system
Macrophages
Online Access:https://doi.org/10.1186/s12951-023-02134-4

Internet

https://doi.org/10.1186/s12951-023-02134-4

Similar Items