Cerebral β-Amyloidosis in Mice Investigated by Ultramicroscopy.

Alzheimer´s disease (AD) is the most common neurodegenerative disorder. AD neuropathology is characterized by intracellular neurofibrillary tangles and extracellular β-amyloid deposits in the brain. To elucidate the complexity of AD pathogenesis a variety of transgenic mouse models have been generat...

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Bibliographic Details
Main Authors: Nina Jährling, Klaus Becker, Bettina M Wegenast-Braun, Stefan A Grathwohl, Mathias Jucker, Hans-Ulrich Dodt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4446269?pdf=render