A modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer’s disease

A modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is a degenerative disorder typified by progressive deterioration of memory and the appearance of β-amyloid peptide (Aβ)-rich senile plaques. Recently we have identified a novel function of a patented formulation of modified Huanglian-Jie-Tu-Tang (HLJDT-M), a Chinese...

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Bibliographic Details
Main Authors: Siva Sundara Kumar Durairajan, Ashok Iyaswamy, Sravan Gopalakrishna Shetty, Ananth Kumar Kammella, Sandeep Malampati, Wenbin Shang, Chuanbin Yang, Juxian Song, Sookja Chung, Jiandong Huang, Kaliappan Ilango, Quan-Bin Han, Min Li
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06217-9

Internet

https://doi.org/10.1038/s41598-017-06217-9

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