A multicenter study of the early detection of synaptic dysfunction in Mild Cognitive Impairment using Magnetoencephalography-derived functional connectivity

Synaptic disruption is an early pathological sign of the neurodegeneration of Dementia of the Alzheimer's type (DAT). The changes in network synchronization are evident in patients with Mild Cognitive Impairment (MCI) at the group level, but there are very few Magnetoencephalography (MEG) studi...

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Main Authors: Fernando Maestú, PhD, Jose-Maria Peña, PhD, Pilar Garcés, MS, Santiago González, PhD, Ricardo Bajo, PhD, Anto Bagic, MD, PhD, Pablo Cuesta, MS, Michael Funke, MD, Jyrki P. Mäkelä, MD, Ernestina Menasalvas, PhD, Akinori Nakamura, MD, Lauri Parkkonen, PhD, Maria E. López, PhD, Francisco del Pozo, PhD, Gustavo Sudre, PhD, Edward Zamrini, MD, Eero Pekkonen, MD, Richard N. Henson, PhD, James T. Becker, PhD
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158215001308