An acetyltransferase effector conserved across Legionella species targets the eukaryotic eIF3 complex to modulate protein translation

ABSTRACTThe survival of Legionella spp. as intracellular pathogens relies on the combined action of protein effectors delivered inside their eukaryotic hosts by the Dot/Icm (defective in organelle trafficking/intracellular multiplication) type IVb secretion system. The specific repertoire of effecto...

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Bibliographic Details
Main Authors: Lukas Syriste, Deepak T. Patel, Peter J. Stogios, Tatiana Skarina, Dhruvin Patel, Alexei Savchenko
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.03221-23