The Ser/Thr phosphatase PP2A regulatory subunit widerborst inhibits notch signaling.

Drosophila Enhancer of split M8, an effector of Notch signaling, is regulated by protein kinase CK2. The phosphatase PP2A is thought to play an opposing (inhibitory) role, but the identity of the regulatory subunit was unknown. The studies described here reveal a role for the PP2A regulatory subunit...

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Bibliographic Details
Main Authors: Anasua Bose, Adam T Majot, Ashok P Bidwai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4090204?pdf=render