Co-expression of DevR and DevR(N)-Aph proteins is associated with hypoxic adaptation defect and virulence attenuation of Mycobacterium tuberculosis.

Co-expression of DevR and DevR(N)-Aph proteins is associated with hypoxic adaptation defect and virulence attenuation of Mycobacterium tuberculosis.

<h4>Background</h4>The DevR response regulator is implicated in both hypoxic adaptation and virulence of Mycobacterium tuberculosis (M. tb). DevR regulon genes are powerfully induced in vivo implicating them in bacterial adaptation to host control strategies. A better understanding of De...

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Main Authors: Shyamasree De Majumdar, Deepak Sharma, Atul Vashist, Kohinoor Kaur, Neetu Kumra Taneja, Santosh Chauhan, Vijay K Challu, V D Ramanathan, V Balasangameshwara, Prahlad Kumar, Jaya Sivaswami Tyagi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20195478/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20195478/?tool=EBI

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