NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation

NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation

Abstract Introduction Nucleoporin 98 (NUP98) fusion proteins are recurrently found in leukemia and are associated with unfavorable clinical outcomes. They are distributed to the nucleus and contribute to leukemogenesis via aberrant transcriptional regulation. We previously identified NUP98‐BPTF (NB)...

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Bibliographic Details
Main Authors: Mina Noura, Sakura Tomita, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Cancer Medicine
Subjects:
cell transformation
leukemia
NUP98‐BPTF
PIM1
RNA‐seq
Online Access:https://doi.org/10.1002/cam4.7445

Internet

https://doi.org/10.1002/cam4.7445

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