High driving pressure ventilation induces pulmonary hypertension in a rabbit model of acute lung injury

High driving pressure ventilation induces pulmonary hypertension in a rabbit model of acute lung injury

Abstract Background Mechanical ventilation may cause pulmonary hypertension in patients with acute lung injury (ALI), but the underlying mechanism remains elucidated. Methods ALI was induced in rabbits by a two-hit injury, i.e., hydrochloric acid aspiration followed by mechanical ventilation for 1 h...

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Bibliographic Details
Main Authors: Yonghao Xu, Yu Zhang, Jie Zhang, Weibo Liang, Ya Wang, Zitao Zeng, Zhenting Liang, Zhaoyi Ling, Yubiao Chen, Xiumei Deng, Yongbo Huang, Xiaoqing Liu, Haibo Zhang, Yimin Li
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Intensive Care
Subjects:
Acute respiratory distress syndrome
Pulmonary hypertension
Mechanical ventilation
Ferroptosis
Online Access:https://doi.org/10.1186/s40560-023-00689-w

Internet

https://doi.org/10.1186/s40560-023-00689-w

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