Mitochondrial Complexes I and II Are More Susceptible to Autophagy Deficiency in Mouse β-Cells

Mitochondrial Complexes I and II Are More Susceptible to Autophagy Deficiency in Mouse β-Cells

BackgroundDamaged mitochondria are removed by autophagy. Therefore, impairment of autophagy induces the accumulation of damaged mitochondria and mitochondrial dysfunction in most mammalian cells. Here, we investigated mitochondrial function and the expression of mitochondrial complexes in autophagy-...

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Bibliographic Details
Main Authors: Min Joo Kim, Ok Kyong Choi, Kyung Sil Chae, Min Kyeong Kim, Jung Hee Kim, Masaaki Komatsu, Keiji Tanaka, Hakmo Lee, Sung Soo Chung, Soo Heon Kwak, Young Min Cho, Kyong Soo Park, Hye Seung Jung
Format: Article
Language:English
Published: Korean Endocrine Society 2015-03-01
Series:Endocrinology and Metabolism
Subjects:
Autophagy
Insulin-secreting cells
Mitochondria
Mitochondrial complex
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-65.pdf

Internet

http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-65.pdf

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